The metabolic health impact of weight loss medications can be significant, primarily through their effects on appetite regulation, energy expenditure, and overall metabolic function. These medications often influence neurotransmitters in the brain, which helps reduce appetite and promote a feeling of fullness. This reduction in appetite can lead to lower caloric intake and, consequently, weight loss. In addition to appetite control, some medications can enhance energy expenditure, promoting higher metabolic rates even at rest. However, it is essential to note that these medications may come with potential side effects, including gastrointestinal issues commonly associated with injectable options. These side effects may include nausea, vomiting, or diarrhea, impacting patient adherence to treatment. To mitigate these side effects, starting at low doses is crucial. This approach allows the body to adjust gradually, minimizing discomfort while achieving long-term metabolic health benefit